Biomedicine Seminar
Professor Søren Riis Paludan: "Novel mechanisms in innate immune defense against virus infections"
Info about event
Time
Location
Ll. Anat. aud., build. 1231, 424 or Zoom ID No: 67993391657
Organizer
Abstract
Pattern recognition receptors (PRRs) are broadly perceived to constitute the first line of defense against infections. While PRRs indeed evoke strong antimicrobial activity, these immune receptors also induce inflammation and are frequently associated with pathologies. This raises the question as to whether additional early immune mechanisms exist, which are less inflammatory and operate independently of PRRs. Interestingly, emerging data from us and others suggest that a panel constitutive and stress-induced immune mechanisms do indeed exert host defense independently of PRRs – and often in a non-redundant manner. These data challenge the current thinking in immunology. In this talk, I will present recent data on novel immune mechanisms in antiviral defense, and will discuss how such data may fit into the larger scheme of how the immune system ensures efficient early host defense without causing pathological inflammatory responses.
ABOUT THE SPEAKER
Søren R. Paludan is Professor at the Department of Biomedicine and heads the newly established DNRF Centre of Excellence “Center for Immunology of Viral Infections (CiViA)”.
The talk is 45 minutes followed by 15 minutes of discussion, for a total of 1 hr.
Remember to sign up for a free sandwich before Monday 27 March
Biomedicine seminar organizing committee
Mikkel Vendelbo
Line Reinert
Søren Egedal Degn
Martin Kristian Thomsen